Circling around that whole web3 ‘ownership’ story.
I have 170k email subscribers. I own the list, entirely. There is no algorithm.
But 60% of my subs are on Gmail. If Gmail flags me as promotional, half my subs won’t see it. And no ownership or composability changes that
^ 🤔 thread
I've been arguing for years that changes in drug use patterns explain a lot of the behavior of the media class in particular for the last 70 years.
Alcohol + tobacco + amphetamines
--> alcohol + weed
--> psychedelics
--> cocaine
...
--> SSRIs + amphetamines + benzos
Marc Andreessen @pmarca
Barbell strategies for life
On taking advantage of both extremes of risk and reward in friendship, caffeination, reading, dating, working, and more:
dwarkeshpatel.com/barbell-strate…
In the simplest multicellular species, bridges are often the only elements connecting cells - suggesting that incomplete abscission can be, in some cases, the very first step towards evolving clonal multicellularity (but not always! biology is complex!)
the most important thing you can do a for someone is raise their ambitions
a friend told me she had agreed to a $50m valuation after turning down another top fund. i told her to go to the other fund and ask them to pay $150m. They did.
3x'ing the value of a co with one call
Amazing to see the raw footage of the first four minute mile and listen to the narration of the athlete himself years later
That McKinsey is being blamed for the wildly optimistic CNN+ subscriber projections is a good insight into why companies hire McKinsey
I bought a Life magazine from 1969, when sugar was advertised for its anti-fattening properties.
Today we chuckle at the ignorance of a culture that could produce such an ad, but, strangely, obesity levels are >3x higher than they were then.
Insightful analysis of the NIH: “the NIH, like all giant bureaucracies, suffers from structural problems that hinder its efficiency and leads to considerable, wasteful spending. The agency is risk-averse and excessively funds an aging cadre of scientists”
^ former Dean of Harvard Medical School on our report.
In October, Pipedream closed a $1.6M pre-seed.
Instead of announcing, we went right to work making underground logistics possible.
Here is what we have been up to since:
(UPDATE MEGA THREAD)
^ wut
The Boring Company just raised $675M at a $5.675B valuation from A-list investors.
Purpose is to recruit amazing people, scale up boring machine production & build thousands of miles of tunnels.
boringcompany.com/seriescround
^ broke: metaverse; woke: literal underground
Y’all are confusing the Fall of the Republic with the Fall of the Empire… we haven’t even gotten to the Empire yet. The Republic lasted for 500 years before the beginning of the Empire. +/- 1 std we are about there. Get ready for the next thousand.
Inpainting with DALL·E 2 is super fun. With some ingenuity, you can create arbitrarily large artwork like the murals shown below – which I assume are the largest #dalle-produced images created so far.
First chart in quarantined section: is there an explanation for 2016 spike?